Does intraperitoneal streptokinase enhance the drainage of loculated ascites in patients with ovarian carcinoma?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN17262544

Enrollment

Registered

2003-09-12

Start date

2000-07-21

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer: Ovarian Cancer Ovarian

Interventions

Arm A: Streptokinase Arm B: Placebo via the peritoneal drain

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Not provided at time of registration

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Net volume of ascitic fluid drained post Streptokinase/saline	—

Secondary

Measure	Time frame
1. Change in abdominal girth 2. Ultrasound estimation of residual fluid (largest fluid pocket) 3. Patient symptomatology (subjective change in discomfort) 4. Time interval to reaccumulation of ascites requiring drainage	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026