The KIdney during surgery for Hip Fracture repair in elderly patients: possible injury due to poor fluid intake and the choice of infusion fluid during the surgery

Kidney injury during hip fracture surgery: a randomized study between crystalloid and colloid fluid and the influence of preoperative dehydration

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN17236125

Enrollment

Registered

2014-06-12

Start date

2014-09-01

Completion date

Unknown

Last updated

2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip fracture surgery Surgery

Interventions

Patients are randomized to receive either 100 ml of Ringer´s acetate solution or 100 ml of 20% albumin during the induction of anaesthesia. Blood and urine sampling is performed on three occasions on

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Males and females with hip fracture who are planned for acute surgery 2. Age range 70-90 years

Exclusion criteria

Exclusion criteria: 1. Kidney disease 2. Serious heart failure (NYHA class III) 3. Those undergoing surgery under general anaesthesia 4. Poor understanding of the Swedish language

Design outcomes

Primary

Measure	Time frame
Changes in urine markers of kidney injury (NGAL, microglobulin, albumin, creatinine and erythrocytes). Urine sampled at baseline and 4 hours after surgery has ended	—

Secondary

Measure	Time frame
1. The effect of albumin and crystalloid fluid on the colloid osmotic pressure, measured at baseline, the beginning of the surgery, and 4 hours after the surgery 2. Surgical complications, measured when the patient leaves the hospital	—

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026