Male infertility Urological and Genital Diseases Male infertility
Conditions
Interventions
Part 1 (Observational component):
Participants will be asked to attend a single visit at the Andrology Unit, Hammersmith Hospital. Visit will take approximately one and half our, and will consist of:
Sponsors
AHSC Joint Research Compliance Office
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Inclusion Criteria (study 1 only) 1. Male 2. 18-60 years of age 3. Participants in the following groups will be recruited: Control Group: Healthy participants Disease Groups: Participants with chronic diseases e.g. diabetes mellitus, obesity Inclusion Criteria (study 2 only) 1. Male 2. Known infertility 3. 18-60 years of age 4. Current lifestyle factors known to affect fertility (e.g. any raised BMI, smoking, recreational drug use, excessive alcohol intake) which remain despite any previous lifestyle advice gained in the NHS
Exclusion criteria
Exclusion criteria: 1. History of anaemia 2. Needle-phobia 3. Acute illness likely to affect the result of study 4. Impaired ability to provide full consent to take part in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Part 1: Sperm count abnormalities will be measured using routine semen analysis at baseline. Part 2: Sperm count abnormalities will be measured using routine semen analysis at baseline, 2, 3, 4 and 5 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Part 2: 1. Weight, measured using scales at baseline, 2, 3, 4 and 5 weeks 2. Serum reproductive hormones using automated immunoassays at baseline, 2, 3, 4 and 5 weeks 3. Serum metabolic parameters using automated immunoassays at baseline, 2, 3, 4 and 5 weeks | — |
Countries
England, United Kingdom
Contacts
Public ContactChanna Jayasena
Outcome results
None listed