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The efficacy of cognitive remediation on processing speed in patients with first episode psychosis

The efficacy of cognitive remediation on processing speed in patients with first episode psychosis: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN17220814
Enrollment
104
Registered
2017-08-17
Start date
2016-08-01
Completion date
Unknown
Last updated
2022-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychosis Mental and Behavioural Disorders Unspecified nonorganic psychosis

Interventions

This single-blinded randomised controlled trial will address the efficacy of CR therapy using NEAR model by targeting processing speed in first episode psychosis. Participants’ cognition, functioning

Sponsors

Public Service Department of Malaysia
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. First-episode psychosis patients with schizophrenia, schizophreniform disorder or schizoaffective disorder at diagnosis and presenting with cognitive deficits 2. Young adults aged 18 to 40 3. Able to read and write in Malay and/or English 4. Written informed consent 5. Fulfil the criteria of cognitive measures, symptomatology and other functioning 6. The symptoms must have been present during the past year including other criteria

Exclusion criteria

Exclusion criteria: 1. Previous diagnosis of mental retardation, psychotic disorder related to a general medical condition or substance-induced psychotic disorder 2. Severe schizophrenia 3. History of any diagnosis of a serious developmental disorder 4. Significant ongoing neurological disorders including epilepsy 5. History of severe head injury 6. Concurrently undergoing other types of cognitive remediation therapy

Design outcomes

Primary

MeasureTime frame
Cognitive functioning, assessed by neurocognitive assessment through The Brief Assessment of Cognition in Schizophrenia (BACS) at baseline and 8 weeks

Secondary

MeasureTime frame
Functional outcomes, assessed using functional measures including Schizophrenia Cognition Rating Scale (SCoRS), Social Functioning Scale (SFS), Social and Occupational Functioning Assessment Scale (SOFAS) and Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4) at baseline and 8 weeks

Countries

Malaysia

Contacts

Public ContactNaniyati Shuib
nani.shuib@gmail.com+60 (0)326 878 168

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026