Healthy active population Other
Conditions
Interventions
The study visit component will take place after the safety screening and participants will have arrived at the lab having not consumed caffeine for 24h. During the entire study visit, participants wil
they will be permitted to read during experiments if desired but will otherwise be quiescent to maximise the validity of heart rate variability data. A blood sample will be performed at the start of t
Sponsors
Defence Science and Technology Laboratory
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Any gender 2. 18-40 years old
Exclusion criteria
Exclusion criteria: 1. An intolerance or avoidance of caffeine 2. Any prescribed medication 3. Long term use of ibuprofen (>6 weeks use in the last 52 weeks) 4. Smokers (smoking defined as more than 100 cigarettes throughout the participant’s lifetime) 5. Current vapers defined as any use in the last 7 days 6. Any consumption of liquorice in the last 7 days 7. Self-declared recreational drug use in the last month including, but not limited to, cannabis and cocaine. No drug testing to be conducted. 8. Self-reported alcohol use within the previous 24 hours 9. Any medical condition that could affect safety or study data at the discretion of the Clinical Research Fellow 10. Phobia to needles or anxiety disorders 11. Allergy or sensitivity to materials used in study (e.g., adhesives) 12. Non-English speakers to ensure informed consent 13. Pregnancy – self-tested using a commercial urine test that will be provided 14. Nursing mothers 15. Atrial fibrillation or other clinically significant arrhythmia 16. Any findings that the Clinical Research Fellow believes affect the integrity of study data or the safety to conduct tests 17. Fever 18. Bladder control issues 19. Bleeding disorders 20. Diabetes 21. Irritable Bowel Syndrome (IBS) 22. Epilepsy 23. Glaucoma 24. Osteoporosis 25. Parkinson’s 26. Schizophrenia 27. History of kidney injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Potassium levels measured via a novel potassium sensor at rest via sweat and blood | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of caffeine administration on physiological response: 1. Electrodermal activity is measured using electrodes on the hand or wrist throughout the 1 hour 30 minute study visit 2. Heart rate variability throughout the 1 hour 30 minute study visit | — |
Countries
England, United Kingdom
Contacts
Public ContactChristopher Gaffney
Outcome results
None listed