Erythema reaction of non-photosensitive individuals to various wavelengths of LED light Skin and Connective Tissue Diseases
Conditions
Interventions
The study will consist of the following interventions and assessments:
Visit 1
Screening/inclusion & exclusion/informed consent
Visit 2 (Day 0) Up to 30 days from Visit 1
1. Non-invasive reflectan
Sponsors
University of Dundee
Eligibility
Sex/Gender
All
Age
18 Years to 999 Years
Inclusion criteria
Inclusion criteria: 1. Healthy persons with no clinically significant abnormality identified by participant reported medical history, in particular no evidence of abnormal photosensitivity 2. Adult males and females, >18 years only 3. Capable of giving informed consent 4. Able to understand and comply with protocol requirements and timetables, instructions and protocol-stated restrictions
Exclusion criteria
Exclusion criteria: 1. Any photosensitising medication or supplement (systemic or topically applied to the test area) within 14 days prior to testing 2. Insufficient clear, untanned, unaffected skin on the back to allow minimal erythema dose (MED) testing 3. Participation in a clinical study involving administration of an investigational drug (new chemical entity/non-licensed drug) or in a clinical study involving administration of a marketed drug within the past 3 months 4. Known to have abnormal photosensitivity 5. Pregnant or breastfeeding 6. Use of self-tanning products on the back (test area) in the preceding 2 weeks 7. Sunbed exposure or natural sunlight-induced sunburn or tan on the back (test area) acquired within the four weeks prior to recruitment 8. Immunosuppression due to medications (such as organ transplant recipient) or disease (including HIV or haematological malignancy) 9. History of skin cancer, not including basal cell carcinoma (BCC) 10. History of malignancy not curatively treated at least 5 years before screening visit, with exception of BCC or cervical carcinoma in situ, which may have been curatively treated within 1 year 11. History of current use of illegal or ‘recreational’ drugs 12. Any condition which, in the opinion of the investigator, might put the subject at risk by participating in this study
Countries
Scotland, United Kingdom
Contacts
Public ContactSusan Yule
Outcome results
None listed