Sudden cardiac death risk evaluation using personalised electrophysiological, autonomic and mental health assessment following myocardial infarction

SUdden death Risk eValuatIon and VulnErability post-Myocardial Infarction

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN17193826

Enrollment

Registered

2026-04-23

Start date

2026-04-30

Completion date

Unknown

Last updated

2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sudden cardiac death following myocardial infarction Circulatory System

Interventions

Suitable patients following MI will be approached alongside controls without cardiac disease to participate in the prospective cohort study. All participants will attend a treadmill exercise study an

subgroups will be determined based on left ventricular ejection fraction. Electrogram and exercise data will be compared between post-MI participants and controls. Validated questionnaires will meas

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Post-MI Inclusion Criteria 1. Patients aged over 18 2. STEMI within 40 days to 3 months Control Inclusion Criteria 1. Over the age of 18 2. Able to consent to the study independently 3. Considered to be fit enough to be able to complete the full repeat measure exercise protocol

Exclusion criteria

Exclusion criteria: Post-MI Exclusion Criteria 1. Diagnosis of a non-ischemic cardiomyopathy 2. Inherited cardiac conditions which have an increased risk of SCD, including inherited structural diseases and channelopathies 3. Presence of severe comorbid conditions limiting life expectancy to less than 1 year 4. Contraindications to exercise study 5. Inability to consent to the study 6. Atrial fibrillation 7. Planned or outstanding coronary percutaneous or surgical revascularisation 8. Deemed unable to participate in an exercise study targeting achievement of maximal heart rate , based on existing functional or symptomatic limitations 9. Inability to understand written and verbal English to enable safe participation on dynamic exercise testing Control Exclusion Criteria 1. Previous cardiac diagnosis including acute coronary syndrome/cardiac surgery, angina, severe valvular heart disease, arrhythmia 2. Previous cardiac intervention including Implanted pacemaker, cardiac surgery 3. Deemed unable to participate in an exercise study targeting achievement of maximal heart rate , based on existing functional or symptomatic limitations 4. Contraindications to exercise study 5. Inability to understand written and verbal English to enable safe participation on dynamic exercise testing

Countries

England, United Kingdom

Contacts

Public ContactEdward Lau

el203@leicester.ac.uk+44 0116 373 6508

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: May 7, 2026