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A study on complete vs. incomplete small bowel examination using single-balloon enteroscopy in obscure gastrointestinal bleeding

Clinical outcomes of complete versus incomplete small bowel examination by single-balloon enteroscopy in obscure gastrointestinal bleeding: a prospective multicenter study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN17191331
Enrollment
450
Registered
2025-04-10
Start date
2025-04-10
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with obscure gastrointestinal bleeding are defined as those who have overt bleeding such as hematemesis, melena, or hematochezia, and have negative results on both upper endoscopy and colonoscopy. Digestive System

Interventions

This study follows patients with obscure gastrointestinal bleeding who undergo either complete or incomplete small bowel examination using single-balloon enteroscopy between January 2016 and December

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. A confirmed diagnosis of obscure gastrointestinal bleeding (OGIB) 2. Admission to one of the following institutions: The First Affiliated Hospital of Zhengzhou University, Henan Provincial People’s Hospital, or Qinghai Provincial People’s Hospital 3. Underwent single-balloon enteroscopy (SBE) between January 2016 and December 2024

Exclusion criteria

Exclusion criteria: 1. Declined to participate in the follow-up 2. Were lost to follow-up during the study period

Design outcomes

Primary

MeasureTime frame
Re-bleeding events, defined as the recurrence of overt gastrointestinal bleeding such as hematemesis, melena, or hematochezia after the initial complete or incomplete single balloon enteroscopy. Clinical presentation, diagnosis, and interventions at the time of re-bleeding are collected from patient records

Secondary

MeasureTime frame
Clinical findings and diagnoses from the initial single balloon enteroscopy, either complete or incomplete, are collected from patient records

Countries

China

Contacts

Public ContactFangbin Zhang
fcczhangfb@zzu.edu.cn(+86)13526655133

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026