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Does add-on therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improve the outcomes of gastric cancer patients?

Evaluation of the adjuvant therapeutic efficacy of Bo-Er-Ning capsule (BENC) in advanced gastric cancer patients by a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN17186893
Enrollment
120
Registered
2018-03-24
Start date
2008-03-15
Completion date
Unknown
Last updated
2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced gastric cancer Cancer Stomach, unspecified

Interventions

All patients with advanced GC treated by FP regimen (Tegafur + Cisplatin) in Zhangqiu People's Hospital of Shandong were enrolled for this clinical study by a doctor participating in the study and ra

Sponsors

Zhangqiu People's Hospital of Shandong
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age from 25 to 75 years 2. All patients were pathologically confirmed for stage IV or postoperative recurrence and metastasis GC 3. Karnofsky performance score (KPS) = 80 4. No previous anticancer therapy 5. No dysfunction of heart, liver, lung and kidney

Exclusion criteria

Exclusion criteria: 1. Age75 years 2. Patients were not pathologically confirmed for stage IV or postoperative recurrence and metastasis GC 3. Karnofsky performance score (KPS) < 80 4. Possess previous anticancer therapy 5. Possess dysfunction of heart, liver, lung and kidney

Design outcomes

Primary

MeasureTime frame
Measured at week 9 (after 3 cycles of chemotherapy): 1. Appetite, assessed by filling out answer sheets 2. Karnofsky performance score (KPS), assessed by filling out answer sheets 3. Body weight, measured using a weight scale

Secondary

MeasureTime frame
3-year overall survival: patients followed up by clinic visit, phone, or mail at least once every 6 months starting from day 1 after the treatment

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026