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The acceptability of seasonal antimalarial medication in Korogho, Côte d'Ivoire

Pilot seasonal malaria chemoprevention implementation in Korogho

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN17164969
Enrollment
1700
Registered
2021-07-02
Start date
2021-07-06
Completion date
Unknown
Last updated
2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria Infections and Infestations Unspecified malaria

Interventions

As part of routine treatment, participants are treated with seasonal malaria chemoprevention (SMC) drugs (unique dose of sulfadoxine-pyrimethamine and one dose of amodiaquine on the first day and two

Sponsors

Institut de Recherche en Sciences de la Santé
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Both sexes 2. Resident of the study area 3. Willingness to remain in the study area during the study 4. Age between 3 and 59 months 5. Provision of signed informed consent 6. Absence of severe malnutrition or severe condition

Exclusion criteria

Exclusion criteria: 1. Absence of provision of informed consent 2. Age less than 3 months and more than 59 months 3. Presence of severe malnutrition or other severe condition 4. Residing outside the study area

Design outcomes

Primary

MeasureTime frame
Proportion of children aged 3 - 59 months (at the time of first SMC cycle) who received five monthly treatments of SMC measured using patient records one month after the last round of treatment (in December)

Secondary

MeasureTime frame
All measured one month after the last round of treatment (in December) unless otherwise noted: 1. The proportion of children 3 - 59 months (at the time of SMC first cycle) who received 1, 2, 3, 4 or 5 monthly treatments of SMC measured using patient records through coverage survey 2. Logistics of delivery including the number of health workers, the time required per month, the average number of children treated per health worker team measured using qualitative and quantitative surveys 3. Timeliness of delivery measured using individual interview 4. Quality of delivery (adherence to guidelines) measured using using individual interview 5. Adherence to supervised and unsupervised doses measured using coverage survey 6. Acceptability to caregivers and to health staff measured using qualitative acceptability questionnaire 7. Prevalence of parasite carriage on baseline and at the end of the fifth cycle measured using epidemiological survey 8. Prevalence of molecular markers conferring resistance to SMC drugs (codons at dhfr, dhps, pfmdr-1 and pfcrt T76) measured using epidemiological survey

Countries

Cote d'Ivoire

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026