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HELPER Programme - cognitive remediation in first episodes of schizophrenia

HELPER Programme (Cognitive Remediation) - a randomised controlled trial of cognitive remediation in first episodes of schizophrenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN17160673
Enrollment
64
Registered
2012-11-02
Start date
2009-01-19
Completion date
Unknown
Last updated
2018-01-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia, Psychosis Mental and Behavioural Disorders Schizophrenia

Interventions

Consenting patients waiting for CBT for psychosis after their first episode of schizophrenia are randomly allocated to either cognitive remediation (CR) or a time-matched social support comparison gro

Sponsors

Lancashire Care NHS Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Participants which they have suffered a 1st episode of psychosis that meets DSM IV criteria for schizophreniform disorder, schizophrenia, schizo-affective disorder, delusional disorder, or psychosis Not Otherwised Specified (NOS) 2. Aged 18 - 35 years 3. Receiving standard care from Early Intervention Service 4. Male and female participants

Exclusion criteria

Exclusion criteria: DSM IV criteria for substance misuse or organic brain disease

Design outcomes

Primary

MeasureTime frame
PSYRATS, a measure of delusions and hallucinations. PSYRATS is reassessed every 6 weeks during the 30week CBT envelope (weeks 12-42). A final PSYRATS is completed at 54 weeks.

Secondary

MeasureTime frame
1. PANSS 2. Calgary Depression 3. Insight Scale and IPQ attitude scores 4. Time to relapse and readmission

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 5, 2026