Sperm quality Urological and Genital Diseases
Conditions
Interventions
Following their usual clinic appointment, participants who meet the eligibility criteria and wish to take part in the study will give their consent and complete a questionnaire about their lifestyle a
Sponsors
Bristol Centre for Reproductive Medicine Limited
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Male 2. Aged between 18-44 years 3. Body mass index (BMI) of at least 18.5 kg/m2 4. Non-smoker 5. Men who have sperm in their ejaculate 6. Non-diabetic 7. No previous eating disorders 8. Participants capable of giving informed consent
Exclusion criteria
Exclusion criteria: 1. A history of eating disorders 2. BMI below 18.5 kg/m2 3. Aged 45 years and over 4. Smoker 5. Men who have no sperm in their ejaculate 6. Diabetic 7. On any medication which needs to be taken with food 8. Previous bariatric surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seminal fluid analysis including concentration, motility and morphology according to WHO guidelines at baseline and 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Testosterone level measured by blood test at baseline and 3 months 2. Metabolomic analysis of seminal fluid collected at baseline and 3 months, using gas chromatography-mass spectrometry (GC-MS) | — |
Countries
England, United Kingdom
Outcome results
None listed