Diabetes mellitus Nutritional, Metabolic, Endocrine Diabetes mellitus
Conditions
Interventions
Enrolled subjects were randomized using a computer generated randomization table. Subjects were randomized to receive Korean red ginseng capsules or placebos for 24 weeks. They were instructed to take
Sponsors
Korea Ginseng Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Men and women between 19 and 75 years of age with Type 2 diabetes on oral antidiabetic agents 2. Diagnosed with Type 2 diabetes more than 6 months ago 3. Unchanged dose or type of antidiabetic agents within the last 3 months
Exclusion criteria
Exclusion criteria: 1. Patients with HbA1c>10% 2. Patients with eGFR 3 times greater the upper normal limit 3. Taking glucocorticoid or any herbal medicine within the past 3 months 4. Chronic inflammatory disease in the active phase or acute infection status 5. Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diabetic microvascular complication markers (estimated glomerular filtration rate (eGFR), urinary albumin to creatinine ratio (uACR), Kidney injury molecule-1 (KIM1), laminin-P1 as a marker for diabetic retinopathy, and current perception thresholds (CPT)), measured at week 24 | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting plasma glucose and HbA1c, measured by blood test at week 24 | — |
Countries
Korea, South
Outcome results
None listed