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Study to establish reference ranges for pregnancy for blood tests

Pregnancy Reference Ranges Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN17018939
Enrollment
1200
Registered
2022-03-07
Start date
2021-04-07
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Looking at normal ranges in healthy pregnancy Pregnancy and Childbirth

Interventions

Women who are pregnant will be asked, as a one off, to given an extra sample of blood at the time that they have routine blood tests in pregnancy, plus in some instances a urine sample at the same tim

Sponsors

Imperial College London
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Women over 18 years of age who are receiving antenatal care at Imperial College London NHS Trust 2. Singleton pregnancies

Exclusion criteria

Exclusion criteria: 1. Multiple pregnancies 2. Current or previous history of thyroid disease 3. Current or previous use of thyroid medications 4. Inability to understand and write in the English Language 5. Unable to participate for other factors as assessed by the Chief Investigators

Design outcomes

Primary

MeasureTime frame
Levels of biochemical analytes in sampled blood will be analysed in accordance with national/international guidance: 1. Thyroid function - TSH, free T3, free T4 2. Thyroid peroxidase antibodies 3. Renin 4. Aldosterone 5. Folate 6. Iron 7. Troponin 8. Iodine

Secondary

MeasureTime frame
Gestation of the pregnancy, the mother’s underlying health, and some demographic data measured at a single time point using a questionnaire

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026