Lung ultrasound to monitor respiratory function in extremely preterm neonates

Lung ultrasound to follow evolution of chronic respiratory insufficiency and predict bronchopulmonary dysplasia in extremely preterm neonates: a multicenter, prospective, pragmatic, observational cohort study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN16987738

Enrollment

100

Registered

2020-05-11

Start date

2017-09-01

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic pulmonary insufficiency of prematurity (CPIP) and bronchopulmonary dysplasia (BPD) Neonatal Diseases

Interventions

Lung ultrasound performed serially every 7 - 14 days in extremely preterm neonates with CPIP and hospitalised in neonatal intensive care units. Based on lung ultrasound findings a lung ultrasound scor

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inborn neonates with gestational age <=30+6 weeks

Exclusion criteria

Exclusion criteria: 1. Complex congenital malformations 2. Chromosomal abnormalities 3. Pulmonary hypoplasia 4. Congenital anomalies of surfactant proteins or any other suspected congenital lung disorders

Design outcomes

Primary

Measure	Time frame
1. Lung aeration in neonates with CPIP using the correlation between lung ultrasound scores (calculated as published by Brat R. JAMA Pediatr 2015) and gas exchange measures performed every 7 - 14 days 2. Bronchopulmonary dysplasia (BPD) at 36 weeks post-menstrual age measured according to clinical criteria (such as need for oxygen or other respiratory support)	—

Countries

France, Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026