Development of a guideline for the early detection of psychosis in long-term care facilities

Unmet care needs among residents of long-term care facilities with moderate to severe psychotic symptoms

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN16976551

Enrollment

1500

Registered

2025-10-16

Start date

2025-09-01

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Older adults in nursing homes with moderate and severe psychotic symptoms Mental and Behavioural Disorders

Interventions

This multicentre, observational study combines cross-sectional and mixed-methods approaches over 1.5 years to inform the development of a practice-oriented clinical guideline for nursing home resident

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The study includes nursing home residents, healthcare professionals, and family members from participating care facilities. There are no specific inclusion criteria beyond residency or professional/family involvement in the care of the residents.

Exclusion criteria

Exclusion criteria: Does not meet the inclusion criteria

Design outcomes

Primary

Measure	Time frame
Prevalence and characteristics of psychotic symptoms measured using the Neuropsychiatric Inventory-Nursing Home version (NPI-NH) and a structured DSM-5-based clinical interview at baseline	—

Secondary

Measure	Time frame
1. Quality of life measured using the WHOQOL-8 questionnaire and semi-structured interviews at baseline 2. Cognitive status measured using the Montreal Cognitive Assessment (MoCA) at baseline 3. Depressive symptoms measured via the NPI-NH, the Cornell Depression Scale and a structured DSM-5-based clinical interview at baseline 4. Pain levels measured using the Doloplus-2 scale at baseline 5. Anxiety symptoms measured via the NPI-NH and a structured DSM-5-based clinical interview at baseline 6. Prevalence and description of missed care identified through a detailed multidisciplinary needs-based analysis and focus groups with professionals, residents, and family members at baseline 7. Prevalence and appropriateness of pharmaceutical care evaluated through a multidisciplinary medication review involving a geriatrician, psychiatrist, neurologist, and pharmacist at baseline	—

Measure

Time frame

1. Quality of life measured using the WHOQOL-8 questionnaire and semi-structured interviews at baseline 2. Cognitive status measured using the Montreal Cognitive Assessment (MoCA) at baseline 3. Depressive symptoms measured via the NPI-NH, the Cornell Depression Scale and a structured DSM-5-based clinical interview at baseline 4. Pain levels measured using the Doloplus-2 scale at baseline 5. Anxiety symptoms measured via the NPI-NH and a structured DSM-5-based clinical interview at baseline 6. Prevalence and description of missed care identified through a detailed multidisciplinary needs-based analysis and focus groups with professionals, residents, and family members at baseline 7. Prevalence and appropriateness of pharmaceutical care evaluated through a multidisciplinary medication review involving a geriatrician, psychiatrist, neurologist, and pharmacist at baseline

—

Countries

Belgium

Contacts

Public ContactHilde Lahaye

hilde.lahaye@odisee.be+32 (0)497593546

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026