Acute effects of electronic cigarette on myocardial function

Acute effects of using an electronic nicotine-delivery device (electronic cigarette) on myocardial function: comparison with the effects of regular cigarettes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN16974547

Enrollment

Registered

2013-08-14

Start date

2012-02-10

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Smoking Mental and Behavioural Disorders

Interventions

We asked smokers to smoke 1 tobacco cigarette for 5 minutes and electronic cigarette users to use an electronic cigarette device for 7 minutes. Echocardiograms were performed, before and after this in

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Clinically healthy individuals 2. No history of cardiovascular or other disease 3. Not taking medications 4. Not pregnant 5. No risk factors for cardiovascular disease (besides smoking)

Exclusion criteria

Exclusion criteria: 1. Electrocardiographic abnormalities 2. Echocardiographic signs of myocardial systolic dysfuntion 3. Low ejection fraction 4. More than mild valve regurgitation or any other valve disease

Design outcomes

Primary

Measure	Time frame
Changes in left ventricular myocardial diastolic function after smoking and electronic cigarette use assessed by echocardiography, 5 minutes after the intervention	—

Secondary

Measure	Time frame
Hemodynamic changes	—

Countries

Greece

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 20, 2026