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Does early removal of breathing support reduce complications in patients who have had surgery for bleeding on the brain?

Fast-track extubation in patients after intracranial hematoma surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN16924441
Enrollment
10
Registered
2019-10-28
Start date
2014-01-31
Completion date
Unknown
Last updated
2020-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early extubation to prevent ventilator-associated complications following intracranial hematoma surgery Respiratory

Interventions

Early extubation, also known as fast track, is desirable after intracranial hematoma surgery to avoid ventilator-associated complications associated with admission to an intensive care unit (ICU). The
extubation was 8

Sponsors

Hospital Universitario "José Eleuterio González"
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients about to receive open cranial surgery due to an intracranial hematoma 2. Anesthesia risk of I-III according to the American Society of Anesthesiologists (ASA) 3. Aged 18 years or over 4. No intubation prior to entering the operating room 5. Glasgow coma score of =8

Exclusion criteria

Exclusion criteria: 1. Patients with catecholamine-secreting tumors, coagulation disorders, or decompensated heart or lung disease 2. Patients with a scheduled surgery in another area of the body 3. Patients with hypovolemic shock 4. Patients whose surgeries lasted for >480 min or were accompanied by massive or uncontrollable bleeding (loss of 50% of blood volume for 3 h (~1 l/h) or >150 ml/kg of body weight or >1.5 ml/kg/min for >20 min

Design outcomes

Primary

MeasureTime frame
Extubation procedure time

Secondary

MeasureTime frame
1. Blood pressure, heart rate, respiratory rate and oxygen saturation measured with an S / 5 anesthesia monitor (GE, Datex / Ohmeda) during the entire surgical procedure and the subsequent 24 h 2. Arterial pH measured every 8 h for 24 h using the Cobas B 221 blood gas analyzer (Roche)

Countries

Mexico

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 19, 2026