Early extubation to prevent ventilator-associated complications following intracranial hematoma surgery Respiratory
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients about to receive open cranial surgery due to an intracranial hematoma 2. Anesthesia risk of I-III according to the American Society of Anesthesiologists (ASA) 3. Aged 18 years or over 4. No intubation prior to entering the operating room 5. Glasgow coma score of =8
Exclusion criteria
Exclusion criteria: 1. Patients with catecholamine-secreting tumors, coagulation disorders, or decompensated heart or lung disease 2. Patients with a scheduled surgery in another area of the body 3. Patients with hypovolemic shock 4. Patients whose surgeries lasted for >480 min or were accompanied by massive or uncontrollable bleeding (loss of 50% of blood volume for 3 h (~1 l/h) or >150 ml/kg of body weight or >1.5 ml/kg/min for >20 min
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extubation procedure time | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Blood pressure, heart rate, respiratory rate and oxygen saturation measured with an S / 5 anesthesia monitor (GE, Datex / Ohmeda) during the entire surgical procedure and the subsequent 24 h 2. Arterial pH measured every 8 h for 24 h using the Cobas B 221 blood gas analyzer (Roche) | — |
Countries
Mexico