A prospective randomised trial to assess the beneficial effect of preoperative hyperoxia therapy on postoperative neuropsychological outcome and inflammatory response after cardiopulmonary bypass

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN16916134

Enrollment

Registered

2003-09-12

Start date

2002-10-07

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular: Cardiopulmonary bypass Circulatory System Cardiopulmonary bypass

Interventions

Randomised controlled trial comparing: 1. Hyperoxia therapy 2. No therapy Study patients will receive the same intra-operative, postoperative and follow-up care as routine patients and as per unit p

Eligibility

Inclusion criteria

Inclusion criteria: A total of 50 patients (25 each group), between 20 and 75 years of age undergoing cardiopulmonary bypass.

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Data collected will be entered into the research department computer and statistical analysis will be done using the Stars Direct Package. Demographics, measures and results of data analysis will be represented as tables, graphs, bar charts and pie charts where applicable. Statistical significance will be set at P-value < 0.05.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026