A pragmatic randomised controlled trial to evaluate physical activity as a treatment for depression

Conditions

Mild/moderate depression Mental and Behavioural Disorders Depression

Panteleimon Ekkekakis, Mark E. Hartman, Matthew A. Ladwig

Journal of Sports Sciences2018-01-1911 citations

10.1080/02640414.2018.1423856

Facilitated physical activity as a treatment for depressed adults: randomised controlled trial.

Chalder M, Wiles NJ, Campbell J, Hollinghurst SP, Haase AM, Taylor AH, Fox KR, Costelloe C, Searle A, Baxter H, Winder R, Wright C, Turner KM, Calnan M, Lawlor DA, Peters TJ, Sharp DJ, Montgomery AA, Lewis G.

2012-06-06118 citations

10.1136/bmj.e2758

A pragmatic randomised controlled trial to evaluate the cost-effectiveness of a physical activity intervention as a treatment for depression: the treating depression with physical activity (TREAD) trial.

Chalder M, Wiles NJ, Campbell J, Hollinghurst SP, Searle A, Haase AM, Taylor AH, Fox KR, Baxter H, Davis M, Thorp H, Winder R, Wright C, Calnan M, Lawlor DA, Peters TJ, Sharp DJ, Turner KM, Montgomery AA, Lewis G.

2012-01-0142 citations

10.3310/hta16100

Interventions

Current interventions as of 10/04/2012 The TREAD intervention aims to increase self-esteem, confidence and social interaction as well as the take-up of physical activity, through the use of motivation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged 18-69 diagnosed by GPs as having a new episode of mild/moderate depression (ICD-10 diagnosis and a score of 14 or more on Beck Depression Inventory)

Exclusion criteria

Exclusion criteria: 1. Physical contraindications to exercise 2. Inability to complete self-administered questionnaires 3. Psychosis 4. Serious drug or alcohol abuse 5. Pregnancy at time of randomisation

Design outcomes

Primary

Measure	Time frame
Current primary outcome measures as of 10/04/2012: Change in clinical symptoms of depression assessed using Beck Depression Inventory at 4-months post-randomisation. Previous primary outcome measures: Change in clinical symptoms of depression assessed using Beck Depression Inventory at 3-months post-randomisation.	—

Secondary

Measure	Time frame
Current secondary outcome measures as of 10/04/2012: A number of secondary outcomes will be measured at various points throughout the trial (4-months, 8-months, 12-months post-randomisation) including change in use of anti-depressants, uptake of physical activity, exercise efficacy and quality of life . Previous secondary outcome measures: A number of secondary outcomes will be measured at various points throughout the trial (3-months, 12-months, 24-months post-randomisation) including change in use of anti-depressants, uptake of physical activity, physical self-perceptions, exercise efficacy, psychiatric co-morbidity, quality of life and social support.	—

Measure

Time frame

Current secondary outcome measures as of 10/04/2012: A number of secondary outcomes will be measured at various points throughout the trial (4-months, 8-months, 12-months post-randomisation) including change in use of anti-depressants, uptake of physical activity, exercise efficacy and quality of life . Previous secondary outcome measures: A number of secondary outcomes will be measured at various points throughout the trial (3-months, 12-months, 24-months post-randomisation) including change in use of anti-depressants, uptake of physical activity, physical self-perceptions, exercise efficacy, psychiatric co-morbidity, quality of life and social support.

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Countries

United Kingdom

Outcome results

None listed