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Comparison of hyperdry amniotic membrane transplantation and conjunctival autografting for primary pterygium

Comparison of hyperdry amniotic membrane transplantation and conjunctival autografting for primary pterygium

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN16900270
Enrollment
140
Registered
2018-05-03
Start date
2015-03-08
Completion date
Unknown
Last updated
2020-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary pterygium Eye Diseases Pterygium

Interventions

One hundred and forty-one eyes from 130 patients with primary pterygium were enrolled in this study. In all cases, the size of the pterygium was at least 2 mm onto the cornea or causing extreme irrita

Sponsors

The Second Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.The size of the pterygium is at least 2 mm onto the cornea or causing extreme irritation. 2. Most of the pterygium is translucent, and the episcleral vessels underneath the body of the pterygium can be identified 3. Patients 30-80 years old

Exclusion criteria

Exclusion criteria: 1. Recurrent pterygium 2. Dry eye 3. Infection and inflammation of ocular area 4. Glaucoma 5. Previous ocular surgery in the study eye 6. Patients with a <6-month follow-up period

Design outcomes

Primary

MeasureTime frame
1. Recurrence defined as the regrowth of the fibrovascular proliferation tissue invading the cornea again, checked at first week and then 1, 3, 6 and 12 months postoperatively

Secondary

MeasureTime frame
1. Visual acuity is measured using a snellen chart at preoperative and postoperative day, first week and then 1, 3, 6, and 12 months postoperatively 2. Intraocular pressure (IOP) measured using a non-contact tonometer at preoperative and postoperative day, first week and then 1, 3, 6, and 12 months postoperatively 3. The size of the pterygium is measured using slit lamp at preoperative day 4. Complications measured using slit lamp at first week and then 1, 3, 6, and 12 months postoperatively 5. Pain is recorded at postoperative day, first week and then 1, 3, 6, and 12 months postoperatively 6. Surgical times, recorded during the surgery

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 6, 2026