Mild to moderate anxiety and depression during pregnancy. Mental and Behavioural Disorders Mild to moderate anxiety and depression during pregnancy.
Conditions
Interventions
Interventions as of 25/07/2016:
Participants will be randomly assigned following simple randomization procedures to 1 of 3 treatment groups. Randomization sequence will be created using R-studio with
Sponsors
Goldsmiths, University of London
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Fluent in English 2. 18-45 years old 3.Singleton pregnancy 4. Mild to moderate depression and anxiety
Exclusion criteria
Exclusion criteria: 1. Serious medical disorder, psychosis, bipolar disorder or drug abuse 2. Severe depression or anxiety
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome as of 25/07/2016: Depression is measured using the The Edinburgh Postnatal Depression Scale (EPDS) at baseline (16-24 weeks gestation), 26 weeks gestation, 32 weeks gestation, and 1, 3 and 6 months postnatal. Original primary outcomes: 1. Depression is measured using the The Edinburgh Postnatal Depression Scale (EPDS) 30 weeks antenatal and 1,3 and 6 months postnatal 2. Anxiety is measured using the Peer Relations Assessment Questionnaires-Revised (PRAQ-R) and The State-Trait Anxiety Inventory (STAI) 30 weeks antenatal and 1,3 and 6 months postnatal 3. Stress is measured using Parenting Stress Index (PSI-4-SF) 30 weeks antenatal and 1,3 and 6 months postnatal 4. Mother Infant bonding is measured using Maternal Antenatal Attachment Scale at 30 weeks antenatal and The Mother-Infant Bonding Scale (MIBS) 1, 3 and 6 months post-natal | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes as of 25/07/2016: 1. Anxiety is measured using the Pregnancy Related Anxiety Questionnaire -Revised (PRAQ-R2) and The State-Trait Anxiety Inventory (STAI) at baseline (16-24 weeks gestation), 26 weeks gestation, 32 weeks gestation and STAI only 1, 3 and 6 months postnatal 2. Stress is measured using Perceived Stress Scale (PSS) at baseline (16-24 weeks gestation), 26 weeks gestation, 32 weeks gestation, and 1, 3 and 6 months postnatal 3. Mother Infant bonding is measured using Maternal Antenatal Attachment Scale at baseline (16-24 weeks gestation), 26 weeks gestation, 32 weeks gestation and Maternal Postnatal Attachment scale (MPAS) and The Mother-Infant Bonding Scale (MIBS) 1, 3 and 6 months postnatal 4. Social support is measured using the Multidimensional Scale of Perceived Social Support (MSPSS) at baseline (16-24 weeks gestation), 26 weeks gestation, 32 weeks gestation and STAI only 1, 3 and 6 months postnatal 4. Infant cognitive and behavioral development is measured using the Infant Behaviour Questionnaire revised (IBQ-R), Bayley Scales of Infant and Toddler Development and the Still Face Procedure at 6 months postnatal 5. Mother's Cortisol and Cytokine levels are measured using saliva samples measured at baseline (16-24 weeks gestation), 32 weeks gestation, and 1 and 6 months postnatal Original secondary outcomes: 1. Infant cognitive and behavioral development is measured using the Bayley Scales and Still Face procedure measured at 6 months after birth 2. Mother's Cortisol and Cytokine levels are measured using a saliva samples measured monthly starting at 30 weeks antenatal, then months 1,3 and 6 postnatal | — |
Countries
United Kingdom
Outcome results
None listed