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Reducing medication-related harm in older people

Implementation of a medicine management plan (MMP) to reduce medication-related harm (MRH) in older people post-hospital discharge: a randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN16864276
Enrollment
684
Registered
2022-05-20
Start date
2022-06-17
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reducing medication-related harm (MRH) in older adults within 8 weeks post-discharge from the hospital Other

Interventions

Participants will undergo simple randomization into the two arms: a control arm and an intervention arm. Participants in the control arm will receive the existing NHS Discharge Medicines Service, whe

Sponsors

University of Sussex
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 120 Years

Inclusion criteria

Inclusion criteria: 1. Patients must be over the age of 65 years at the time of recruitment, admitted to an acute Elderly Care or General Medical Ward 2. Patients to be identified when they are likely to be discharged within 48 hours 3. Patients need to be registered with a General Practitioner within the areas covered by the recruiting hospitals 4. Informed written consent must be provided from patients with capacity OR personal consultees acting on behalf of patients without capacity

Exclusion criteria

Exclusion criteria: 1. Patients lacking capacity and have no consultee to advise 2. Patients that are transferred to other acute healthcare trusts (but excluding step down or intermediate care facilities) 3. Patients who have a short life expectancy, due to a terminal illness 4. Patients who are unable to read/speak/understand English

Design outcomes

Primary

MeasureTime frame
The number of participants that had medication-related harm who had only the NHS-discharge medicines services (DMS) and the number of participants with medication-related harm who had both the NHS-DMS with the medicines management plan (MMP), measured using a phone interview at the end of the 8-week period

Secondary

MeasureTime frame
1. The acceptability of the control and intervention arm among clinicians, service providers, researchers and other health workers involved in discharge planning assessed through focus group interviews during the study period 2. The cost-effectiveness of the intervention will be measured using economic analysis estimating the resources involved in delivering the intervention and treatment of medication-related harm within 8 weeks post-discharge

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 7, 2026