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Is it necessary to add chlorhexidine to a glass-ionomer restorative?

Survival of occlusal ART restorations with and without chlorhexidine containing high-viscosity glass-ionomer: a 2-year split-mouth quadruple-blind randomized controlled clinical pilot trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN16774328
Enrollment
100
Registered
2018-02-04
Start date
2008-01-15
Completion date
Unknown
Last updated
2018-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental cavitated teeth Oral Health Dental caries

Interventions

Considered a pilot study, a convenient sample size of 100 students per treatment group was chosen. Randomization of the two restoratives over the prepared cavities was performed as follows: 100 identi

Sponsors

Dental School University of Cairo
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Healthy patients without a history of any medical disease or condition that could interfere with the study protocol or affect clinical results 2. Patients without oral habits that could affect the study results 3. Presence of natural antagonist 4. Presence of at least two teeth with a cavitated dentine carious lesions in an occlusal surface in first or second permanent molars situated in different sides of the jaw 5. Occlusal cavities with size (Site/Stage 1.2 or 1.3) 6. Absence of apparent enamel crack or fracture 7. No pulp involvement or symptoms of pulpitis or apical periodontitis

Exclusion criteria

Exclusion criteria: 1. Poor oral hygiene 2. Deciduous teeth 3. Patients declaring daily consumption of substantial volume of citric juices

Design outcomes

Primary

MeasureTime frame
Development of secondary carious lesions, assessed using the USPHS criteria at baseline, 6, 12,18 and 24 months

Secondary

MeasureTime frame
Quality of the restorations, assessed using ART restoration criteria at baseline, 6, 12,18 and 24 months

Countries

Egypt

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026