Adolescent idiopathic scoliosis (AIS). Musculoskeletal Diseases Juvenile idiopathic scoliosis
Conditions
Interventions
Measurements previously collected from adolescents with AIS will be compared to age and gender matched controls to determine if there are any differences between the two groups, which may indicate alt
Sponsors
University of Warwick
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adolescents (aged 10-16) with no known spinal pathology or neurological conditions
Exclusion criteria
Exclusion criteria: 1. Individuals that have suffered significant back pain or other musculoskeletal conditions requiring time off school or sporting activity, or requiring treatment from a health professional in the preceding 12 months 2. Individuals with significant spinal or trunk asymmetry which may indicate the presence of scoliosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Images of the trunk/back in different orientations will be used to test laterality discrimination ability in both control and AIS participants. Laterality discrimination is the ability to identify right from left sides of the body and is measured by accuracy (% correct) and reaction time (seconds) to reach a correct decision. When viewing images of specific body parts in different positions, a correct response requires selection of left or right side, then a mental spatial transformation to confirm the choice. Accurate and timely response is dependent on an intact body representation. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Two point discrimination (2PD). If the two points of a compass are simultaneously applied to the skin, they will normally be perceived as separate stimuli. However, below a certain threshold distance (normally measured in millimetres), this ability is lost and instead the two points will be perceived as only one stimulus. As a test of tactile spatial acuity, 2PD depends in part on the integrity of the cortical representation of the body area being tested. 2. Tactile localisation discrimination involves determining the location of stimulation. Patients are shown a picture of the back with marked locations and are then asked to report which point was stimulated. Accuracy of response depends on an intact body schema and changes in localisation ability have been reported as being associated with cortical reorganisation and symptom reduction in chronic pain conditions. 3. Proprioception using a position matching protocol. Participants will be asked to sideflex the trunk in sitting to a point in mid-range and then, once returned to the upright position, to return to the same position where any differences will be measured. 4. Midline judgement using line bisection tests. A series of horizontal lines will be presented to the participant who will attempt to mark the centre of each one. Differences between the estimated and actual centres, along with direction, will be measured. 5. One legged standing balance. A timed test of how long subjects can maintain one leg standing without having to seek support. 6. Kinaesthetic and Proprioception Assessment Questionnaire (KPAQ). A 12 item self-report measure of proprioceptive and movement awareness (5 point likert scale). 7. Other measurement tools such as the EQ5D, a measure of self-reported function (Paediatric Outcomes Data Collection Instrument, PODCI) and demographic information will also be collected along with height, weight and puberty status. 8. Modified versions of scoliosis specific questionnaires such as the SRS-22 | — |
Countries
United Kingdom
Contacts
Public ContactPeter Heine
Outcome results
None listed