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Virtual reality-assisted cognitive behavioral therapy for conflict-affected adolescents in Gaza: a low-intensity mental health intervention

A two-arm randomized controlled trial evaluating the effectiveness of virtual reality-assisted cognitive behavioral therapy compared to standard CBT in reducing PTSD symptoms among conflict-affected adolescents in Gaza

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN16685192
Enrollment
42
Registered
2025-08-08
Start date
2025-08-06
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-Traumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD) symptoms, Acute psychological distress (anxiety, fear, stress), emotional dysregulation and impaired well-being in conflict-affected adolescents, mental health impacts of chronic trauma and armed conflict in Gaza Mental and Behavioural Disorders

Interventions

Participants will be randomly assigned to the intervention (VR-assisted CBT) or control (CBT-only) group using a computer-generated block randomization scheme, stratified by gender to ensure balanced

Sponsors

University of California, San Diego
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adolescents aged 12-18 years 2. Clinical or subclinical PTSD symptoms 3. Residing in the Gaza refugee camps 4. Consent and assent obtained 5. Able to commit to sessions

Exclusion criteria

Exclusion criteria: 1. Active psychosis 2. Severe developmental delay 3. Physical impairments affecting VR use 4. Currently undergoing other psychological interventions

Design outcomes

Primary

MeasureTime frame
PTSD symptoms measured using the International Trauma Questionnaire (ITQ) at baseline, 6 weeks (post-intervention), and 14 weeks (2-month follow-up)

Secondary

MeasureTime frame
1. Psychological distress (depression, anxiety, and stress) measured via the Depression, Anxiety, and Stress Scale (DASS-21, Arabic version) at baseline and post-intervention (6 weeks) 2. Treatment satisfaction assessed with the Treatment Satisfaction Scale at post-intervention only (6 weeks)

Countries

Palestine, State of

Contacts

Public ContactRawan Iriqat
ririqat@health.ucsd.edu+1 (0)8584051478

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026