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Steroid induction regimen for juvenile idiopathic arthritis

Steroid induction regimen for juvenile idiopathic arthritis (SIRJIA): a multicentre feasibility trial

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN16649996
Enrollment
16
Registered
2016-02-03
Start date
2018-06-20
Completion date
Unknown
Last updated
2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Juvenile idiopathic arthritis Musculoskeletal Diseases Juvenile arthritis

Interventions

The trial will comprise of a literature review, a prospective study to collect observational data (to inform a possible future RCT), a survey of healthcare professionals on current practice, qualitati

Sponsors

Alder Hey Children’s Foundation NHS Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with JIA and their parents/carers will be eligible to take part in the qualitative research aspect of the trial

Exclusion criteria

Exclusion criteria: Patients aged under 8 years and patients/carers residing more that one days' travel away from the primary research site (Liverpool)

Design outcomes

Primary

MeasureTime frame
Develop outcomes of the feasibility study including a report to HTA with assessment of the proposed intervention and control arms for definitive study

Secondary

MeasureTime frame
1. A comprehensive assessment of current UK practice as regards JIA CS treatment, and potential trial capability and acceptability (by conducting a national survey) 2. Ascertainment of HCP views on the most appropriate patient group(s) and control and intervention arms (through a stakeholder consensus meeting) 3. A qualitative study of parent and patient perspectives in relation to a future RCT of CS 4. The choice of a primary outcome measure for a clinical trial in children and young people with JIA (through literature review, Delphi process and stakeholder consensus meeting) 5. Undertake a prospective feasibility study for the early induction of remission in children and young people with JIA testing chosen primary outcome, treatment arms and JIA subgroups to be studied

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 18, 2026