Nutrition-related suboptimal foetal development and growth Pregnancy and Childbirth Slow foetal growth and foetal malnutrition
Conditions
Interventions
A randomised factorial experiment was conducted to evaluate effects of food and mirconutrient supplements during pregnancy on health outcomes of the women and their newborn infants. There were two foo
Sponsors
International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B) (Bangladesh)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Women (aged 14 - 50 years) in the study area (Matlab) with pregnancy confirmed by urine test and ultrasound with gestational age less than 14 weeks.
Exclusion criteria
Exclusion criteria: Chronic disease that prevented participation in the trial or planned emigration from the area.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Size at birth, measured within 72 hours 2. Gestational age at birth 3. Infant mortality, prospectively assessed up to 1 year of age 4. Maternal haemoglobin and micronutrient status in third trimester, measured at 30 weeks of gestation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Growth, measured every month up to 1 year, thereafter every 3 months to 24 months and at 4.5 years, and cognitive development, measured at 7 months, 18 months and 4.5 years 2. Micronutrient status, measured at 6 months and 4.5 years of age 3. Immune function, measured at 4.5 years of age, and morbidity, measured monthly with 1-week recall up to 1 years, thereafter 3-monthly up to 2 years and at 4.5 years 4. Blood pressure at 4.5 years 5. Metabolic markers at 4.5 years 6. Mothers are followed with anthropometry into the next pregnancy (when applicable), measured 6 months after delivery when becoming pregnant again | — |
Countries
Bangladesh
Outcome results
None listed