Influence of tissue graft substitute in the treatment of gingival recessions

Treatment of multiple adjacent gingival recessions with interproximal attachment loss with an acellular dermal matrix and apical buccal access. Randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN16572455

Enrollment

Registered

2024-08-21

Start date

2024-08-28

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple adjacent gingival recessions with interproximal attachment loss Oral Health

Interventions

The study will be a prospective randomized clinical trial with a follow-up of 12 months. Patients presenting multiple adjacent gingival recessions with interproximal attachment loss (RT3 from Cairo et

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients = 18 years old 2. Periodontally and systemically healthy 3. Patients presenting multiple (at least 2) adjacent gingival recessions with interproximal a9achment loss - RT3 gingival recessions from Cairo et al 2011 Classification, including gingival recessions in upper and lower maxilla from premolar to premolar area. 4. Full mouth plaque score and full mouth bleeding score = 20% (measured at four sites per tooth) 5. The patient must be able to perform food oral hygiene

Exclusion criteria

Exclusion criteria: 1. Contraindications for periodontal surgery or systemically unhealthy 2. Patients pregnant or attempting to get pregnant 3. Uncontrolled periodontal disease 4. Gingival recessions in the molar area 5. Single gingival recession

Design outcomes

Primary

Measure	Time frame
Complete coverage of the recession measured using a periodontal probe, intra-oral scanning file (STL) and digital software overlapping different files at 6 and 12 months	—

Secondary

Measure	Time frame
1. Esthetic score measured using using numeric values from 0 to 10 at 6 months and 1 year 2. Patient-reported postoperative pain measured using a VAS scale at 2 weeks 3. Patient satisfaction measured using a VAS scale at 1 year 4. Keratinized tissue width (KTW) gain measured in mm using a manual periodontal probe at 6 months and 1 year 5. Keratinized tissue thickness (KTT) measured in mm using an intra-oral scanning file (STL) and digital software at 6 months and 1 year 6. Professional-reported esthetics measured by a blinded examiner using numeric values from 1 to 5 at 6 months and 1 year	—

Measure

Time frame

1. Esthetic score measured using using numeric values from 0 to 10 at 6 months and 1 year 2. Patient-reported postoperative pain measured using a VAS scale at 2 weeks 3. Patient satisfaction measured using a VAS scale at 1 year 4. Keratinized tissue width (KTW) gain measured in mm using a manual periodontal probe at 6 months and 1 year 5. Keratinized tissue thickness (KTT) measured in mm using an intra-oral scanning file (STL) and digital software at 6 months and 1 year 6. Professional-reported esthetics measured by a blinded examiner using numeric values from 1 to 5 at 6 months and 1 year

—

Countries

Spain

Contacts

Public ContactErik Regidor

erik@ortizvigon.com944158902

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026