Schizophrenia, schizotypal and delusional disorders Mental and Behavioural Disorders
Conditions
Interventions
This is a single-arm pilot feasibility and acceptability study. There will be no comparison group
all participants recruited in the study will be offered the intervention.
Recruitment:
Individuals will be recruited via CAMHS across the four SLaM boroughs (Croydon, Lambeth, Lewisham and Southwark
Sponsors
King's College London
Eligibility
Sex/Gender
All
Age
13 Years to 18 Years
Inclusion criteria
Inclusion criteria: Adolescents must: 1. Aged 13 to 18 years 2. Living at home with either one or both parents, carers, or legal guardians 3. Diagnosed with schizophrenia or “unspecified schizophrenia spectrum and other psychotic disorder” according to established diagnostic instruments - K-SADS-PL, or SCID depending on the age, diagnosed with “major depression with psychotic features” or “bipolar disorder with mood congruent psychotic features” according to established DSM-5 criteria 4. Have at least one negative symptom according to NSA-4 5. Be currently allocated to a mental health team within SLaM Parent/ Carer participants must: 1. Be the parent, carer or legal guardian of the adolescent participant 2. Be living at home with the adolescent
Exclusion criteria
Exclusion criteria: Adolescents must: 1. Be able to independently understand and provide spoken and written responses during study procedures 2. Not be diagnosed with an established neurological developmental disorder, which would mean that they are unable to engage with the intervention 3. Not be participating in other research projects involving psychological intervention for psychosis 4. Be able to independently understand and provide spoken and written responses during study procedures 5. Not be diagnosed with an established neurological developmental disorder, which would mean that they are unable to engage with the intervention 6. Not be participating in other research projects involving psychological intervention for psychosis Parent/ Carer participants must: 1. Be able to independently understand and provide spoken and written responses during study procedures 2. Not be diagnosed with an established neurological developmental disorder, which would mean that they are unable to engage with the intervention 3. Not be participating in other research projects involving psychological intervention for psychosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acceptability of the intervention measured using individual semi-structured post-intervention interviews, based on the Theoretical Framework of Acceptability (TFA), and the Experience of Service Questionnaire (ESQ) at the end of the intervention;Feasibility measured using data collected on the percentage of participants that 1) express interest in/ are referred to the study, 2) are eligible to take part, 3) consent, 4) complete/drop-out from the intervention at the end of the intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Negative symptoms measured using the Clinical Assessment Interview for Negative Symptoms (CAINS) at baseline and end of intervention;Overall severity of illness measured using the Clinical Global Impression – Severity scale (CGI-S) at baseline and end of intervention;Level of functionality measured using the Global Assessment of Functioning scale (GAF) at baseline and end of intervention;Depressive symptoms measured using the Montgomery-?sberg Depression Rating Scale (MADRS) at baseline and end of intervention;Manic symptoms measured using the Young Mania Rating Scale (YMRS) at baseline and end of intervention;Wellbeing measures measured using the Warwick-Edinburgh Mental Well-being Scale (WEMWBS) at baseline and end of intervention;Quality of life measured using the Quality of Life Scale (QOLS) at baseline and end of intervention;Involuntary movements measured using the Abnormal Involuntary Movement Score (AIMS) at baseline and end of intervention;Healthcare resource use, comprising the number of adolescent hospital admissions, number of days of psychiatric hospitalisation, medications, and number of visits to the emergency department measured using data collected from patient medical records at the end of the study;Feasibility of the intervention, comprising the percentage of participants who 1) attend the enrolment session and 2) complete pre- and post-intervention measured using questionnaires and interviews at post-intervention | — |
Countries
England, United Kingdom
Contacts
Public ContactMariam Shah
Outcome results
None listed