Prevention of PTSD and depression, including subsyndromal PTSD and depression. Mental and Behavioural Disorders PTSD and depression
Conditions
Interventions
Participants complete questionnaires about depression and post-traumatic stress. They are not able to take part if the questionnaires suggest that they may have one of these problems and would benefit
Sponsors
University of Oxford
Eligibility
Sex/Gender
All
Age
18 Years to 120 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 and above 2. In years 1, 2 or 3 of student paramedic training 3. Access to internet 4. Willing to be randomly allocated
Exclusion criteria
Exclusion criteria: Current symptoms of PTSD or Major Depression requiring treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Diagnoses of post-traumatic stress disorder (PTSD) and major depression (MD) are measured using the Structured Clinical Interview for DSM-5 – PTSD and MD modules at baseline, six weeks, one and two year follow up 2. PTSD and MD symptomatology are measured using the PTSD Symptom Checklist (PCL-5) and the Patient Health Questionnaire (PHQ-9) at baseline, six weeks, six months and one and two year follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Resilience is measured using the Connor Davidson Resilience Questionnaire (CD-RISC) and the Resilience Scale (Wagnild & Young, 1993) at baseline, six weeks and one and two year follow-up 2. RRumination is measured with the Ruminative Response Scale (brooding subscale) and the dwelling subscale of the RIQ at baseline, six weeks, and one and two year follow-up 3. Responses to intrusive memories are measured using the Response to Intrusions Questionnaire (RIQ) at baseline, six weeks and one and two year follow-up 4. Symptoms of anxiety are measured using the Generalized Anxiety Disorder 7-item Scale (GAD-7) at baseline, six weeks and one and two year follow-up 5. Smoking and alcohol use are measured with the Smoking and Alcohol Use (unpublished) at baseline, six weeks, and one and two year follow-up 6. Weight and height are measured with the Weight and Height Questionnaire (unpublished) at baseline, six weeks and one and two year follow-up 7. Sleep quality and duration is measured with the Insomnia Severity Index at baseline, six weeks and one and two year follow-up 8. Psychological distress is measured with the General Health Questionnaire (GHQ-12) at baseline, six weeks and one and two year follow-up 9. Well-being is measured with the WEMWBS at baseline, six weeks and one and two year follow-up 10. Levels of cortisol will be assessed by ELISA assay analysis on samples collected upon awakening, 15, 30, and 60 minutes after awakening, and at 12 noon and 8 pm at baseline, six weeks, and one and two year follow-up 11. High sensitivity C-reactive protein levels will be measured using an enzyme-linked immunosorbent assay in fasting serum samples collected at baseline, six weeks and one and two year follow-up 12. Quality adjusted life years are determined with the EuroQoL (EQ-5D-5L) administered at baseline, six weeks, one and two year follow-up 13. Costs associated with psychiatric illness are being measured with the Trimbos/iMTA Questionnaire for Costs associated with | — |
Countries
United Kingdom
Contacts
Public ContactJennifer Wild
Outcome results
None listed