The evaluation of heart muscle changes in muscular dystrophies applying cardiac magnetic resonance: follow-up study

Cardiac involvement in muscular dystrophies assessment by cardiovascular magnetic resonance: follow up study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN16491505

Enrollment

Registered

2017-11-29

Start date

2017-04-10

Completion date

Unknown

Last updated

2021-11-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with a genetically confirmed diagnosis FSHD Type 1 and PROMM who took part in a previous studies Musculoskeletal Diseases FSHD Type 1 and PROMM

Interventions

Participants receive a detailed work up (including an ECG, Holter and Echocardiogram) by a cardiologist. The participants undergo a CMR. They receive the same CMR protocol as during the previous study

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: FSHD and PROMM patients who took part in the previous study PROMM 2013, FSHD 2015/2016

Exclusion criteria

Exclusion criteria: 1. Known vascular, cardiac diseases (e.g. coronary artery disease, significant valvular disease, myocarditis) 2. Malign diseases or known contraindications for CMR 3. Gadolinium-based contrast-media

Design outcomes

Primary

Measure	Time frame
Increase of myocardial tissue injuries is measured using magnetic resonance imaging visually looking for presence and extent of lesions like fat and scar as well as diffuse myocardial changes at yearly follow up.	—

Secondary

Measure	Time frame
Heart rhythm disturbances is measured using ECG and ECG monitoring at yearly follow up	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 20, 2026