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Fluorescence-guided lymphatic mapping in colorectal cancer

Indocyanine green fluorescence-guided lymphatic mapping and navigated lymphadenectomy in colorectal cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN16454797
Enrollment
240
Registered
2025-06-17
Start date
2018-08-01
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ICG-guided lymphadenectomy in left-sided colorectal cancer Cancer

Interventions

• ICG-Guided Group (Experimental Arm): Patients received real-time indocyanine green (ICG) near-infrared fluorescence imaging-guided central lymph nodes mapping and dissection during laparoscopic radi

Sponsors

Peking University People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 85 years 2. Pathologically confirmed left-sided colon or rectal adenocarcinomas 3. Legal competence

Exclusion criteria

Exclusion criteria: 1. Coexisting untreated malignancies 2. Medically contraindications to laparoscopic surgery 3. Known allergy to ICG or iodine 4. Impaired liver function

Design outcomes

Secondary

MeasureTime frame
1. Total number of lymph nodes retrieved, measured via pathological analysis (postoperative day 0) 2. Surgical safety, assessed by intraoperative and postoperative complication rate within 30 days, based on clinical records and follow-up visits 3. 3-year disease-free survival (DFS), measured by clinical and radiological follow-up at regular intervals (every 3–6 months) 4. 3-year overall survival (OS), assessed through hospital records and follow-up calls at 36 months

Primary

MeasureTime frame
Number of central lymph nodes harvested, measured by pathological examination of surgical specimens postoperatively at day 0

Countries

China

Contacts

Public ContactYudi Bao
ydbao@pku.edu.cn+86 13810355879

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026