Effect of pre-exposure prophylaxis (PrEP) on risky sexual behaviours of female sex workers in Dakar, Senegal

Randomized controlled trial of the effect of pre-exposure prophylaxis on risky sexual behaviours of female sex workers in Dakar, Senegal

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN16445862

Enrollment

500

Registered

2021-03-11

Start date

2021-07-01

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention of HIV and other sexually transmitted infections (STIs) Infections and Infestations Human immunodeficiency virus [HIV] disease, Infections with a predominantly sexual mode of transmission

Interventions

The study randomises respondents into a treatment arm and a control arm. This randomisation is stratified according to two criteria: 1) prior use of PrEP and 2) self-reported risk preferences in sex.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Female sex workers who participated in the July 2020 survey wave of a female sex worker panel survey 2. Female sex workers who in the July 2020 survey wave responded that they are still doing sex work

Exclusion criteria

Exclusion criteria: If it was recorded in any of the past three survey waves held in 2015, 2017 and 2020 that the female sex workers has a medical record that indicates seropositive status

Design outcomes

Primary

Measure	Time frame
Measured with a survey expected to be held 3 months after the roll-out of PrEP: 1. Condom use with each of the last two clients and the last five clients measured via a combination of these methods: 1.1. Via direct questioning 1.2. Via list experiment 1.3. Via a newly-designed instrument aimed at eliciting individual condom use without compromising respondent confidentiality 2. Subjective perceptions of the necessity of condom use measured using a Likert-like scale	—

Measure

Time frame

Measured with a survey expected to be held 3 months after the roll-out of PrEP: 1. Condom use with each of the last two clients and the last five clients measured via a combination of these methods: 1.1. Via direct questioning 1.2. Via list experiment 1.3. Via a newly-designed instrument aimed at eliciting individual condom use without compromising respondent confidentiality 2. Subjective perceptions of the necessity of condom use measured using a Likert-like scale

—

Secondary

Measure	Time frame
Measured with a survey expected to be held 3 months after the roll-out of PrEP: 1. Number of occasional and regular clients seen in a fixed time frame, e.g. 7 days 2. Perceived HIV risk of clients 3. Price of each of the last two clients 4. Type of sex acts with last two clients/stayed overnight with last two clients 5. Earnings from sex work in a fixed time frame, e.g. 30 days 6. Household expenditure in a fixed time frame, e.g. 30 days 7. Food insecurity 8. Self-reported STI symptoms with last two clients 9. Mental health measured using the PHQ-9 questionnaire	—

Measure

Time frame

Measured with a survey expected to be held 3 months after the roll-out of PrEP: 1. Number of occasional and regular clients seen in a fixed time frame, e.g. 7 days 2. Perceived HIV risk of clients 3. Price of each of the last two clients 4. Type of sex acts with last two clients/stayed overnight with last two clients 5. Earnings from sex work in a fixed time frame, e.g. 30 days 6. Household expenditure in a fixed time frame, e.g. 30 days 7. Food insecurity 8. Self-reported STI symptoms with last two clients 9. Mental health measured using the PHQ-9 questionnaire

—

Countries

Senegal

Contacts

Public ContactAurélia Lépine

a.lepine@ucl.ac.uk+44 (0)20 7905 2646

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026