Cognitive decline Mental and Behavioural Disorders
Conditions
Interventions
The study was conducted as a randomized controlled trial with a crossover design. Due to the physical nature of the intervention involving physical compression of the muscles during blood flow restric
Sponsors
Singapore Institute of Technology
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Healthy young adults aged 18 to 35 years 2. Recreationally active (at least two times of physical activity per week) 3. No prior experience of training in BFR-related exercises
Exclusion criteria
Exclusion criteria: 1. Any cardiovascular or clotting disorders* 2. Any conditions contraindicated to cycling 3. Taking of any medications that influence heart rate and blood pressure such as beta-blockers, diuretics or ACE inhibitors 4. Deep vein thrombosis 5. Peripheral vascular disease 6. Nerve entrapments in hip region *Examples: Coronary artery disease, arrythmias (abnormal heart rhythm), peripheral vascular disease, congenital heart disease, haemophilia, Von Willebrand disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Working memory, selective attention, and executive function were assessed using cognitive assessments (namely Stroop test and Digit Span) performed at baseline before exercise and after exercise | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Blood lactate measured via a finger prick test using a handheld lactate analyzer at baseline before exercise and after exercise 2. Rating of perceived exertion self-reported using Borg scale at baseline before exercise, after each sprint interval, and after exercise 3. Cycling power output measured via the Monark Bike software during the whole duration of the exercise 4. Respiratory variables including VO2, VCO2 and respiratory exchange ratio measured with a metabolic cart (Quark COSMED) during the whole duration of the exercise | — |
Countries
Singapore
Contacts
Public ContactXiang Ren Tan
Outcome results
None listed