Lyme disease Infections and Infestations
Conditions
Interventions
The study will follow patients for up to 12 months without altering their standard treatment. Participants will be recruited from primary care settings when they present with suspected Lyme disease an
Sponsors
University of Liverpool
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. GP identified patients who are being treated on clinical suspicion of Lyme disease. 2. Patients 18 years of age or over 3. Availability and willing to attend further appointments for blood/urine samples and complete patient questionnaires. 4. Capacity to provide informed consent to participate in the study 5. Self-caring and mobile
Exclusion criteria
Exclusion criteria: 1. Contraindication to blood sampling 2. Extreme frailty and/or comorbidity with poor life expectancy 3. Long term antibiotic use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measured using patient records unless noted: 1. Antibiotic treatment duration and patient compliance over 12 months 2. EM rash resolution with standard treatment over 12 months 3. Longitudinal symptom and severity reporting (Patient Reported Outcome) over 12 months 4. Serology evolution and profile at baseline, 3 and 6 months 5. Microbiological status (skin biopsy subgroup) at diagnosis 6. Patient reported outcomes post-baseline up to 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
England, United Kingdom
Contacts
Public ContactRampy Kumar
Outcome results
None listed