Pain in Paget's disease

Deciphering the mechanisms of pain in Paget's disease of bone

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN16335935

Enrollment

250

Registered

2021-06-14

Start date

2019-06-09

Completion date

Unknown

Last updated

2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paget's disease of bone (PDB) Musculoskeletal Diseases Paget disease of bone

Interventions

The study involves a single visit lasting approximately 90 minutes which involves blood samples being taken, questionnaires being answered and quantitative sensory testing being undertaken to compare

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Clinical diagnosis of PDB 2. Age of 18 years or older 3. Willing and able to give informed consent

Exclusion criteria

Exclusion criteria: 1. Unable to comply with study procedures.

Design outcomes

Primary

Measure	Time frame
Pain is measured using the BPI questionnaire and a visual analogue scale (VAS) at a single time point	—

Secondary

Measure	Time frame
QST will measure sensory detection and pain thresholds above affected and unaffected bone at a single time point	—

Countries

England, Scotland, United Kingdom, Wales

Contacts

Public ContactKathryn Berg

kathryn.berg@ed.ac.uk+44 (0)1316518726

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026