The effect of sheep ghee on pain of the knee joint in older people with osteoarthritis of the knee

The effect of sheep ghee on pain, stiffness, physical function, and range of motion of the knee joint in older people with osteoarthritis of the knee

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN16332782

Enrollment

Registered

2025-03-07

Start date

2021-09-01

Completion date

Unknown

Last updated

2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Assessing changes in knee joint stiffness, pain, range of motion, and physical function after the use of ghee in elderly people affected by osteoarthritis. Musculoskeletal Diseases

Interventions

The intervention group applied 1g (equivalent to a small ice cream spoon) of sheep ghee on painful areas (front, side, and back) of the knee twice daily in the morning and at night for a month. A food

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. No injury, open wound or skin disease in the knee 2. No recent injury to the affected knee 3. No alcohol or drug addiction 4. No use of other complementary methods such as physiotherapy, acupuncture or percutaneous electrical nerve stimulation 5. No history of knee surgery 6. Insensitivity to Vaseline and sheep ghee 7. No mental illness and cognitive disorder 8. Ability to see and walk 9. Ability to communicate 10. Mild to moderate pain score in VAS (Visual Analogue Scale) 11. No history of intra-articular corticosteroid or hyaluronic acid injection for the past three months

Exclusion criteria

Exclusion criteria: Not meeting the participant inclusion criteria

Design outcomes

Primary

Measure	Time frame
Pain is measured using the Visual Analogue Scale (VAS) before and immediately after the intervention	—

Secondary

Measure	Time frame
1. The range of motion for the knee joint is measured using the distance from the heel to the thigh with a ruler before and immediately after the intervention 2. The condition of patients with knee osteoarthritis, including pain, stiffness, and physical functioning of the joints, is measured using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) before and immediately after the intervention. This questionnaire evaluates three subscales on a Likert scale (None, Mild, Moderate, Severe, Extreme): 1) assessment of knee pain over the past 48 hours, 2) joint stiffness, and 3) physical function in the last 48 hours.	—

Measure

Time frame

1. The range of motion for the knee joint is measured using the distance from the heel to the thigh with a ruler before and immediately after the intervention 2. The condition of patients with knee osteoarthritis, including pain, stiffness, and physical functioning of the joints, is measured using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) before and immediately after the intervention. This questionnaire evaluates three subscales on a Likert scale (None, Mild, Moderate, Severe, Extreme): 1) assessment of knee pain over the past 48 hours, 2) joint stiffness, and 3) physical function in the last 48 hours.

—

Countries

Iran

Contacts

Public ContactHadi Khoshab

hadikhoshab@gmail.com+989132425700

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026