Carbon monoxide poisoning Injury, Occupational Diseases, Poisoning Accidental poisoning by and exposure to other gases and vapours
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or older 2. Presenting to the ED with symptoms suggestive of cardiac chest pain, non-traumatic headache, flu-like symptoms unless suggestive of specific focus of infection, seizures or syncope/presyncope
Exclusion criteria
Exclusion criteria: 1. Aged under 18 years 2. Chest pain associated with chest wall tenderness or non-cardiac cause (pulmonary embolism, pneumothorax) 3. Recurrent situational syncope 4. Head injury 5. Actual or suspected smoke inhalation 6. Unable to understand the informed consent process and/or has a poor understanding of English (e.g. English-speaking relative/translator not available within timescales for study procedures) 7. Patients previously enrolled in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carboxyhemoglobin (COHb) level in blood sample provided on day of presentation to Emergency Department | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Answers to questions in the COMA screening questionnaire provided by patient on day of presentation to Emergency Department 2. Time of year of confirmed or suspected CO exposure (summer versus winter) assessed using patient medical records and gas engineer data following presentation 3. Diagnosis of dementia during the 28 days following presentation assessed using patient medical records | — |
Countries
England, United Kingdom