Paranoia Mental and Behavioural Disorders
Conditions
Interventions
Design
Randomised Controlled trial, randomising 144 participants to either a 10-week group mindfulness therapy alongside their usual treatment (n=72) or treatment as usual alone (n=72).
Measures
Part
Sponsors
University of Southampton
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Have a diagnosis of a Schizophrenia Spectrum Disorder, or attending an Early intervention in Psychosis Service, and be experiencing current distressing persecutory delusions (confirmed by clinical team psychiatrist). 2. Be aged over 18 years of age. 3. Be able to provide informed consent to take part.
Exclusion criteria
Exclusion criteria: 1. Participants will not have an identified organic cause for their symptoms 2. Diagnosis of a learning disability. 3. Participants with a significant risk of violence to others
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression – measured by the PHQ9 at baseline, after the therapy (4 months post-randomisation), and at follow-up (8 months post-randomisation) | — |
Secondary
| Measure | Time frame |
|---|---|
| At baseline, post therapy (approx. 4 months post randomisation) and follow up (approx. 8 months post randomisation): 1. Recovery – measured by the Recovery Assessment Scale 2. Anxiety – measured by the GAD-7 3. Psychotic symptoms – measured by the PSYRATS 4. Forgiveness – measured by the Trait Forgivingness Scale 5. Loneliness – measured using the UCLA Loneliness Scale (3-item version) 6. Mindfulness – measured by the Southampton Mindfulness Questionnaire 7. Health economic measures – including CRSI, EQ-5D-5L, and ReQOL-10 | — |
Countries
England, United Kingdom
Contacts
Public ContactLyn Ellett
Outcome results
None listed