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Early feeding versus routine feeding after tumor removal using Ivor Lewis minimally invasive esophagectomy

A randomized clinical trial to assess early feeding versus routine feeding for patients who undergo Ivor Lewis minimally invasive esophagectomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN16281941
Enrollment
120
Registered
2020-02-19
Start date
2020-03-01
Completion date
Unknown
Last updated
2020-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative feeding after esophageal resection Surgery

Interventions

Patients were randomly allocated by a computer-generated random number list to receive EOF policy (when to eat depending on patients’ willingness) or LOF (feeding on 7 days after surgery). All the pat
if there is no discomfort, on the second day slag-free liquid diet will be received, each time 20-50 ml
if there is no discomfort, on the three day after feeding, transition to a semi-flow diet, mainly porridge, 200 ml each time.

Sponsors

Second Affiliated Hospital of Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged =18 years 2. Undergoing minimally invasive Ivor Lewis intervention with intrathoracic anastomosis for esophageal cancer

Exclusion criteria

Exclusion criteria: 1. Age = 80 years 2. Exploratory surgery 3. Bilateral recurrent laryngeal nerve (RLN) injury 4. Patients with other malignancies

Design outcomes

Primary

MeasureTime frame
Number of hospital stays after operation. The discharge criteria are: ability to tolerate a soft diet, no signs of a postoperative complication that needed to be treated at the hospital, ability to ambulate without assistance, tolerable pain on oral analgesia and assessed by the attending doctor

Secondary

MeasureTime frame
1. Quality of life, measured using the European Organization for Research and Treatment of Cancer (EORCT) assessed within 3 days prior to surgery, 2 weeks , 4 weeks and 3 months after operation 2. General quality of life questionnaire (C30) and OES18 assessed within 3 days prior to surgery, 2 weeks , 4 weeks and 3 months after operation 3. Time in the ICU, morbidity (graded based on the Clavien–Dindo classification) 4. Mortality within 30 days

Countries

China

Contacts

Public ContactMing Wu
iwuming22@zju.edu.cn+86 13757118715

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026