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Evaluating how artificial intelligence affects clinicians’ decisions when interpreting wrist X-rays

A multi-reader multi-case study of clinician performance with, and without artificial intelligence assistance for wrist fracture detection, with embedded qualitative study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN16251539
Enrollment
22
Registered
2026-01-29
Start date
2026-02-18
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wrist fracture Injury, Occupational Diseases, Poisoning

Interventions

This is a multi-reader multi-case (MRMC) study evaluating clinician interpretation of wrist radiographs with and without artificial intelligence (AI) decision support. Participating clinicians will i

Sponsors

University of Oxford
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Wrist imaging: 1. Adult patients (18 years or older) who have had a x-rays of the hand/wrist for suspected fracture at Oxford University Hospitals NHS Foundation Trust, 2010-2022. Readers: 1. Clinicians who interpret wrist and/or hand radiographs as part of routine clinical practice. 2. Healthcare professionals (advanced nurse practitioners and doctors) who currently work, have worked, or will work (within 1 year of the study) in emergency departments, minor injuries units, radiology, musculoskeletal trauma services in the United Kingdom. 3. Able to provide informed consent. 4. Able to attend the study session and use the study software.

Exclusion criteria

Exclusion criteria: 1. Clinicians who do not routinely interpret wrist or hand radiographs. 2. Inability to provide informed consent. 3. Prior involvement in the development, training, validation, or evaluation of the AI system used in the study. 4. Prior access to, or knowledge of, the reference standard labels for the study cases. 5. Any conflict of interest or role that could reasonably compromise independent interpretation of cases (e.g. involvement in case selection or ground-truth annotation).

Countries

England, United Kingdom

Contacts

Public ContactRachel Kuo
rachel.kuo@ndorms.ox.ac.uk+44 (0)1865 227374

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 4, 2026