Alginate formulations for enhancing colonic health

A physiological study to assess the acceptability of daily alginate (Manucol LD) consumption in healthy volunteers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN16202716

Enrollment

Registered

2015-01-28

Start date

2015-04-01

Completion date

Unknown

Last updated

2019-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

This physiological study aims to look at the acceptability of consuming a daily alginate which is thought to improve colonic health. Digestive System

Interventions

Objectives 1. To evaluate the acceptability of supplementation of Manucol LD in healthy subjects for 28 days. 2. To explore the benefit of Manucol LD on bifidobacteria.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy male or female participants aged 18 years or above 2. In the opinion of the investigator, capable of complying with the study requirements and completing the study 3. Willing and able to give informed consent

Exclusion criteria

Exclusion criteria: Participants who have a current or previous history of gastrointestinal disease will not be eligible to take part in the study.

Design outcomes

Secondary

Measure	Time frame
1. Effect of Manucol LD on quality of life measured over the 1 month period using the SF36 questionnaire 2. Level of bifidobacteria (a bacterium associated with gut health) in stool	—

Primary

Measure	Time frame
General acceptability of Manucol LD by the end of the study period	—

Countries

United Kingdom

Contacts

Public ContactTariq;Pritesh Iqbal;Mistry

;

t.h.iqbal@bham.ac.uk;p.mistry.1@bham.ac.uk07713 575156;0121 414 2228

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026