Use of 3-helium MRI scanning to determine efficacy of chest physiotherapy in cystic fibrosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN16158695

Enrollment

Registered

2007-09-28

Start date

2006-08-17

Completion date

Unknown

Last updated

2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cystic fibrosis Nutritional, Metabolic, Endocrine Cystic fibrosis

Interventions

We have previously shown that 3-helium MRI scanning provides a reliable and reproducible means of imaging the chest of CF. The technique is well tolerated in children as young as 5 years and can show

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with CF 2. Aged <5 years 3. Able to perform spirometry

Exclusion criteria

Exclusion criteria: Patients undergoing a significant respiratory exacerbation sufficient to prevent lung function testing.

Design outcomes

Primary

Measure	Time frame
Change in dynamic lung function as demonstrated by 3-helium MR scanning, post chest physiotherapy	—

Secondary

Measure	Time frame
Further demonstration of the use of 3-helium scanning to relate structural to functional change in the lung	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026