Does personalised care planning improve the quality of life of older people with frailty and is it cost-effective?

PROSPER: A definitive, multi-site, individually randomised controlled trial of PeRsOnaliSed care Planning for oldER people with frailty

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN16123291

Enrollment

1337

Registered

2020-08-28

Start date

2021-01-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Older people with frailty Other

Interventions

The study is a multi-centre, individually randomised trial with clustering in the intervention arm. The researchers will aim to recruit 1337 older people with frailty from general practices across fiv

Eligibility

Sex/Gender

All

Age

65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. eFI score of 0.21 or above 2. Aged 65 years or over 3. Willing and able to give informed consent (or personal consultee if lack capacity)

Exclusion criteria

Exclusion criteria: 1. Care home resident at the time of screening 2. Registered on the gold standards framework 3. Severe cognitive impairment (Montreal Cognitive Assessment score <10)

Design outcomes

Primary

Measure	Time frame
Health-related quality of life measured using the Physical Component Summary (PCS) and Mental Component Summary (MCS) of the Short-Form 12 item Health Questionnaire (SF12) at 12 months post-randomisation	—

Secondary

Measure	Time frame
1. Basic and instrumental activities of daily living, measured using the Nottingham Extended Activities of Daily Living Scale (NEADL) at 12 months post-randomisation 2. Admissions to care homes and overall health and social care resource use, measured by participant-reported and routine data derived resource use at 12 months post-randomisation 3. Cost-effectiveness measured using decision analytical cost-effectiveness model at 12 months post-randomisation 4. Generalisability of PCP across the wider NHS measured using a mixed-methods process evaluation at 3 months post-randomisation: 4.1. Assessment of intervention fidelity by examining training & skill acquisition, intervention delivery, content of care sessions, receipt and enactment using observations, qualitative interviews and quantitative data 4.2. Process of implementation within the service context explored using a combination of qualitative observations, semi-structured interviews and documentary analysis	—

Measure

Time frame

1. Basic and instrumental activities of daily living, measured using the Nottingham Extended Activities of Daily Living Scale (NEADL) at 12 months post-randomisation 2. Admissions to care homes and overall health and social care resource use, measured by participant-reported and routine data derived resource use at 12 months post-randomisation 3. Cost-effectiveness measured using decision analytical cost-effectiveness model at 12 months post-randomisation 4. Generalisability of PCP across the wider NHS measured using a mixed-methods process evaluation at 3 months post-randomisation: 4.1. Assessment of intervention fidelity by examining training & skill acquisition, intervention delivery, content of care sessions, receipt and enactment using observations, qualitative interviews and quantitative data 4.2. Process of implementation within the service context explored using a combination of qualitative observations, semi-structured interviews and documentary analysis

—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 4, 2026