A Randomised Controlled Trial to Assess the Effectiveness and Cost Effectiveness of TURP, Laser and Watchful Waiting in the Treatment of Bladder Outflow Obstruction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN16113281

Enrollment

106

Registered

2004-01-23

Start date

1994-01-10

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder outflow obstruction in men Urological and Genital Diseases Obstructive and reflux uropathy

Interventions

1. Laser therapy with a noncontact, side firing neodymium:YAG probe 2. TURP (standard transurethral prostatic resection) 3. Watchful waiting (conservative management, including monitoring without acti

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Men with uncomplicated lower urinary tract symptom that is not acute or chronic urinary retention.

Exclusion criteria

Exclusion criteria: Does not match inclusion criteria

Design outcomes

Primary

Measure	Time frame
1. International Prostate Symptom Score (I-PSS) 2. Maximum urinary flow rate 3. A composite measure of success based on I-PSS and maximum urinary flow rate categories 4. I-PSS quality of life score 5. Post-void residual urine volume	—

Secondary

Measure	Time frame
1. Treatment failure 2. Hospital stay 3. Major complications.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026