Weaning from mechanical ventilation Surgery
Conditions
Interventions
Patients are blindly allocated to undergo a 1-hour spontaneous breathing trial with either automatic tube compensation (ATC) (patients breathed through the ventilatory circuit using flow-triggering an
Sponsors
Rabin Medical Center (Israel)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age range 18 - 76 years, either sex, in the intensive care unit 2. Have required mechanical ventilation for greater than 24 hours 3. Meet criteria for weaning: 3.1. Improvement of the cause of respiratory failure 3.2. Oxygen saturation greater than 92% with a fraction of inspired oxygen (FiO2) of less than 50% 3.3. Stable neurological status (Glasgow Coma Score [GCS] greater than 8) 3.4. Require bronchial toilet less than twice in the 8 hours preceding the assessment 3.5. No need for vasoactive drugs 3.6. Receiving only minimal or no sedation 3.7. Body temperature greater than 36°C and less than 38°C 3.8. Level of pressure support less than 15 cm H2O with a positive end-expiratory pressure (PEEP) level of 8 cm H2O or less
Exclusion criteria
Exclusion criteria: Does not comply with the above inclusion criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tolerance of the spontaneous breathing trial: ability to maintain spontaneous breathing for greater than 48 hours after extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Predictive value of the frequency to tidal volume ratio with ATC compared to the ratio without ATC. | — |
Countries
Israel
Outcome results
None listed