Is it beneficial to give chemotherapy before surgery in patients with advanced ovarian cancer?

Is interval debulking surgery as effective as primary debulking surgery for locally advanced epithelial ovarian cancer?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN16064304

Enrollment

Registered

2020-10-02

Start date

2017-10-17

Completion date

Unknown

Last updated

2020-10-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian cancer Cancer Malignant neoplasm of ovary

Interventions

Patients in the primary debulking surgery arm underwent surgical exploration with the intent of having no residual tumor. The surgical procedure included total abdominal hysterectomy, bilateral salpin

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients with locally advanced epithelial ovarian cancer

Exclusion criteria

Exclusion criteria: 1. Patients with stage I and II tumors 2. Non-epithelial histology or borderline tumors 3. Underwent surgical interventions outside the trial institute

Design outcomes

Primary

Measure	Time frame
Retrieved from operative notes in patient medical records at the end of patient stay: 1. Operative time 2. Procedure performed 3. Need for blood transfusion 4. Post operative complications	—

Secondary

Measure	Time frame
Progression free survival assessed using imaging and lab tests every 6 months up to 18 months	—

Countries

Egypt

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026