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Feasibility of home urine collection for lung health check

Feasibility of home urine collection for lung health check (P4-LHC)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN16053507
Enrollment
1000
Registered
2026-08-04
Start date
2025-08-15
Completion date
Unknown
Last updated
2026-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer Cancer

Interventions

NHS staff in the TLHC at Liverpool Heart and Chest Hospital will identify 1000 subjects for the University of Liverpool to approach for the study. The chosen subjects represent three major groups for
with unknown risk (unless they subsequently engage with TLHC, as is hoped). 2. TLHC low-risk responders: 250 randomly selected from those who are low risk for lung cancer according to TLHC risk scores
store them in a secure database
create their own Liverpool University Biobank (LUB) Subject ID
and produce a personalised package for each subject approached consisting of: 1. An introductory leaflet (one page) with invite letter on the back (specific to the subject group) 2. A participant info

Sponsors

University of Liverpool
Lead Sponsor

Eligibility

Sex/Gender
All
Age
55 Years to 75 Years

Inclusion criteria

Inclusion criteria: Prior invitation to the Cheshire and Merseyside NHS Lung Cancer Screening Programme (at the time called Targeted Lung Health Check [TLHC]) as identified by Liverpool Heart and Chest Hospital

Exclusion criteria

Exclusion criteria: 1. Not included in the NHS Targeted Lung Health Check recruitment or opted out of NHS data sharing 2. Unable to provide consent

Design outcomes

Primary

MeasureTime frame
Re-engagement in the NHS Lung Cancer Screening Programme measured using updated recruitment data to Lung Cancer Screening (LCS) at 6 months from initial recruitment invite

Secondary

MeasureTime frame
GAGome biomarker measured using quantitative high-performance liquid chromatography (HPLC) at following end of recruitment

Countries

England, United Kingdom

Contacts

Public ContactMichael Davies
michael.davies@liverpool.ac.uk+44 (0)151 794 9105

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Sep 19, 2026