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Evaluation of the role of saliva in the diagnosis of disease

Evaluation of the role of saliva in the diagnosis of oral and systematic diseases (a case-control study)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN16047134
Enrollment
70
Registered
2023-10-11
Start date
2018-10-10
Completion date
Unknown
Last updated
2023-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Evaluation of saliva role in diagnosis of oral cancer, lichen planus, aphthous stomatitis and celiac disease. Oral Health

Interventions

Patients were included after performing an oral and histological examination to confirm the diagnosis of specific disease and obtaining a written consent from each patient. In addition, demographic de

Sponsors

Damascus University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age is over 18 years old 2. Oral squamous cell carcinoma, lichen planus, recurrent oral stomatitis, celiac disease.

Exclusion criteria

Exclusion criteria: 1. Systemic diseases: such as diabetes, cardiovascular disease, renal disease, liver disorders and hypertension 2. On regular medications 3. Suffers from any mental disorder or any physical disability

Design outcomes

Primary

MeasureTime frame
Measured at a single time point: 1. In the lichen planus group, cortisol was measured using an ELIZA test and then the amount of optical absorbance is measured at a wavelength of 450nm. 2. In the oral cancer group LDH was measured using the Hitachi 911 automated clinical chemistry analyzer, utilizing pyruvate as a substrate at 37 ºC. 3. In both aphthous stomatitis and celiac disease groups IgA was measured using the Hitachi 912 machine.

Secondary

MeasureTime frame
There are no secondary outcome measures

Countries

Syria

Contacts

Public ContactAliaa Alshaar
aliaa.alshaar@damascusuniversity.edu.sy+963 958909620

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026